Teratogenicity results when drugs are given during____________?
(A) First trimester
(B) Second trimester
(C) Third trimester
(D) Soon after birth
Therapetic index indicates____________?
(A) Drug toxicty
(B) Drug potency
(C) Drug safety
(D) Drug’s Lethal effect
The ratio of the median lethal dose of the median effective dose is the_____________?
(A) Morbidity index
(B) Moratality index
(C) Anesthetic ratio
(D) Therapeutic index
Km value indicates______________?
(A) Purity of Enzyme
(B) Physiological role
(C) Half life enzymes drug complex
(D) Affinity
Plasma concentration of drug at time 0 is 96g/mL. if t1/2 is 2 hours concentration is plasma at 10 hours will be___________?
(A) 48
(B) 24
(C) 12
(D) 3
A prodrug is____________?
(A) The proto type member of a class of drugs
(B) The oldest member of a class of drugs
(C) An inactive drug that is transformed in the body to an active metabolite
(D) A drug that is stored in body tissues and is then gradually released in the direction
IF patient suffered from exaggerated effect of pharmacological effect____________?
(A) Idosyncrasy
(B) Toxicity
(C) Side effect
(D) None of the above
Majority of drugs are transported across the membrane by____________?
(A) Passive diffusion
(B) Active transport
(C) Facilitated trasnsport
(D) Filtration
Elimination after 4 half lives in first order kinetics is____________?
(A) 84%
(B) 93%
(C) 80.5%
(D) 4.75%
What is the advantage of sublingual route of administration of drugs_____________?
(A) prevents or bypasses first pass effects
(B) Easy to administer
(C) Lipid soluble
(D) Can be spitted out with signs of toxicity